Diffusion measurements also characterize interactions of ions and proteins with the chondroitin and heparan sulfate components of the extracellular matrix however, the many roles of the matrix are only starting to become apparent. Imaging the spread of macromolecules shows them increasingly hindered as a function of size and suggests that the gaps between cells are predominantly ∼40 nm with wider local expansions that may represent dead-spaces. Monte Carlo modeling indicates that geometrical constraints, including dead-space microdomains, contribute to the hindrance to diffusion.
A point-source paradigm, realized in the real-time iontophoresis method using tetramethylammonium, as well as earlier radiotracer methods, have shown that the extracellular space occupies ∼20% of brain tissue and small molecules have an effective diffusion coefficient that is two-fifths that in a free solution. Attempts to reveal the size and structure of the extracellular space using electron microscopy have had limited success however, a biophysical approach based on diffusion of selected probe molecules has proved useful. The space provides a reservoir for ions essential to the electrical activity of neurons and forms an intercellular chemical communication channel. It contains a solution that closely resembles cerebrospinal fluid with the addition of extracellular matrix molecules. You’re hardcore.Brain extracellular space is the narrow microenvironment that surrounds every cell of the central nervous system. He flies into the control panel, gets electrocuted, and shorts out the power supply. She pretends to be injured then hits a guard with an EPIC kick. Several armed security guards arrive, but Dr. Noel heads to the main power supply, so that she can shut it down despite a major risk of electrocution.
Tantalus V has that giant firewall shield preventing Spock and other backup from beaming down to help. She decides to redeem herself by opening up a giant can of whoop ass. Noel has been a nuisance of a character, picking fights with Kirk and then trying to plant fake romantic memories in her mind. I gotta admit, this scene really impressed me. Helen escape through a conveniently-located ventilation shaft. Luckily, Kirk’s brain is made of stronger stuff, and he quickly remembers the truth. For a split second, Kirk thinks that he’s actually in love with Dr. Noel and Kirk are tossed into a locked room. Sacrifice your career, your reputation.”Īfter the torture, Dr.
Adams turns the brain beam to full power, causing Kirk excruciating pain, and suggests “You’re madly in love with Helen. Her heterosexual storytime is interrupted by Dr. I wonder what Spock would think about all this. She tells Kirk that he’s hungry, and he’s instantly ready to “raid a kitchen.” When Kirk instructs her to make a more complex suggestion, she goes off into romance novel fantasy-land, brainwashing Kirk into thinking that they’ve been in love for years!
Kirk asks her to make a suggestion the next time she uses the mind whammy. Whenever she switches it on, his face goes lax and he has no recollection and he forgets everything during those moments. What a brilliant and not at all dangerous plan! He sits down and instructs Dr. Kirk’s still suspicious about the Neural Neutralizer (wonder if there’s a patent on that), and he decides to play lab rat with Dr. I’m not sure if the mind meld is a super power I’d like to have. It seems as though Spock is sharing in the doctor’s torment, as they speak in unison. “Our mind is so empty, like a sponge, needing thoughts. If you try and remember anything, you’re hit with a fuckton of pain. Adams is erasing people’s brains and writing his own thoughts in there. Van Gelder calms down and enters a trance. Van Gelder’s head and presses on a bunch of nerves.ĭr.
Van Gelder keeps warning them about how the Neural Neutralizer is terrible and “like death.” He’s having a really hard time speaking, and he keeps writhing around in pain, the poor dude.īones begs Spock to use a super-secret Vulcan technique known as the “mind meld.” Hooray! I love Spock exposition episodes! He grasps Dr. Meanwhile, Bones and Spock are wringing their hands, because the tormented Dr. She tells Kirk, “I can assure you that the doctor hasn’t created a chamber of horrors here.” Adams - perhaps because he’s really famous for revolutionizing the prison system. Adams says, “Part of our cure is to bury the past!” Hmmm, that sounds super safe!ĭr. So why’s everyone in such a weirdo mood? Well one of the Doc’s failed experiments, called the “Neural Neutralizer,” is supposed to calm violent patients with the power of suggestion. The 200 Best Lesbian, Bisexual & Queer Movies Of All Time.LGBTQ Television Guide: What To Watch Now.